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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
16.97
Human Site:
S561
Identified Species:
24.89
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S561
F
A
R
L
R
P
Q
S
P
G
V
P
M
Q
T
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S690
F
A
R
L
R
P
Q
S
P
G
V
P
M
Q
T
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S561
F
A
R
L
R
P
Q
S
P
G
V
P
M
Q
T
Dog
Lupus familis
XP_854926
772
85603
S562
F
A
R
L
R
P
Q
S
P
A
G
P
M
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S561
F
A
R
L
R
P
Q
S
P
A
E
P
M
Q
T
Rat
Rattus norvegicus
Q63531
735
82865
V523
L
Y
T
I
S
K
T
V
E
Y
L
H
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
P491
G
F
A
R
L
K
P
P
D
N
Q
P
L
K
T
Chicken
Gallus gallus
Q5F3L1
789
89022
P564
G
F
A
R
L
K
P
P
D
N
Q
P
L
K
T
Frog
Xenopus laevis
P10665
733
82620
V521
L
F
T
V
C
K
T
V
E
N
L
H
S
Q
G
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
G532
V
D
Y
L
H
C
Q
G
V
V
H
R
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
K773
N
N
R
F
K
S
W
K
D
K
P
R
Y
T
L
Honey Bee
Apis mellifera
XP_395099
910
102507
R593
F
G
F
A
R
I
K
R
G
C
E
P
L
H
T
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
Q540
E
Q
Q
L
K
S
V
Q
V
L
R
K
M
T
P
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
P534
R
I
T
N
S
N
Q
P
L
K
T
P
C
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
D263
E
K
G
I
M
H
R
D
L
K
P
E
N
I
L
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
K469
D
V
I
Y
R
D
L
K
P
E
N
I
L
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
13.3
13.3
6.6
13.3
N.A.
6.6
26.6
13.3
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
20
N.A.
26.6
26.6
20
13.3
N.A.
13.3
40
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
32
13
7
0
0
0
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
0
7
7
0
0
0
7
0
0
7
0
0
% C
% Asp:
7
7
0
0
0
7
0
7
19
0
0
0
7
0
7
% D
% Glu:
13
0
0
0
0
0
0
0
13
7
13
7
0
0
0
% E
% Phe:
38
19
7
7
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
13
7
7
0
0
0
0
7
7
19
7
0
0
0
13
% G
% His:
0
0
0
0
7
7
0
0
0
0
7
13
0
7
0
% H
% Ile:
0
7
7
13
0
7
0
0
0
0
0
7
0
7
0
% I
% Lys:
0
7
0
0
13
25
7
13
0
19
0
7
0
13
7
% K
% Leu:
13
0
0
44
13
0
7
0
13
7
13
0
25
13
13
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
38
0
0
% M
% Asn:
7
7
0
7
0
7
0
0
0
19
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
32
13
19
38
0
13
57
0
0
7
% P
% Gln:
0
7
7
0
0
0
44
7
0
0
13
0
0
44
0
% Q
% Arg:
7
0
38
13
44
0
7
7
0
0
7
13
0
0
0
% R
% Ser:
0
0
0
0
13
13
0
32
0
0
0
0
13
0
7
% S
% Thr:
0
0
19
0
0
0
13
0
0
0
7
0
0
13
50
% T
% Val:
7
7
0
7
0
0
7
13
13
7
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
7
0
0
0
0
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _